منابع مشابه
Models of Visceral Nociception.
Pains arising from the viscera constitute a large portion of clinically treated pains. They are characterized by poor localization; immobility with tonic increases in muscle tone; and vigorous but nonspecific changes in autonomic function, such as changes in respiration, heart rate, and blood pressure. Tissue-damaging stimuli do not reliably produce visceral pain, so the study of visceral nocic...
متن کاملPostoperative Models of Nociception.
Even though it is a costly, poorly understood problem, very little effort has been dedicated toward research on the mechanisms of acute postoperative pain. Presumably, if we learn more about the etiology of acute incisional pain and the sensory processes that intensify pain after surgery, new treatment methods can be advanced. Since the mid-1990s, our group and others have developed and charact...
متن کاملAnimal models of nociception.
The study of pain in awake animals raises ethical, philosophical, and technical problems. We review the ethical standards for studying pain in animals and emphasize that there are scientific as well as moral reasons for keeping to them. Philosophically, there is the problem that pain cannot be monitored directly in animals but can only be estimated by examining their responses to nociceptive st...
متن کاملCentral effect of histamine on acetic acid-induced visceral nociception in rats
In the present study, the effects of intracerebroventricular (ICV) injections of histamine, chlorpheniramine (H1-receptor antagonist) and ranitidine (H2-receptor antagonist) were investigated on visceral nociception induced by an intraperitoneal (IP) injection of acetic acid in rats. The latency time to the beginning of the first abdominal wall contraction (the first writhe) was recorded and th...
متن کاملNeuroanatomy of visceral nociception: vagal and splanchnic afferent.
Afferent fibres convey sensory information from the upper gastrointestinal tract to the central nervous system but the nature of this information is different for vagal and spinal pathways. Vagal afferents convey predominantly physiological information while spinal afferents are able to encode noxious events. Because of the different response profiles following activation of these pathways, it ...
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ژورنال
عنوان ژورنال: ILAR Journal
سال: 1999
ISSN: 1084-2020
DOI: 10.1093/ilar.40.3.119